Calculate f1 and f2 Dissolution Values in Excel — Accurately and Instantly.
The validated Excel add-in for pharmaceutical scientists. Automate your dissolution analytics without learning new software or compromising data security.
Automate your dissolution workflow.
The Problem with Manual f1/f2 Calculations
Writing f1 and f2 formulas manually in an Excel sheet looks straightforward. In practice, there are at least four ways to get the wrong answer:Syntax Errors: Misplaced or missed parentheses that completely alter the result.Regulatory Misses: Forgetting to exclude time points where Rt > 85% (the 85% rule).Data Drift: Rounding values inconsistently between different steps in the calculation.Blind Spots: No CV check, meaning non-qualifying data gets included without warning.
The troubling part: Excel produces a number either way. You won’t always know when something is wrong.Stop Second-Guessing Your f2 Formula.
Determine values for f1 difference and f2 similarity factors in a fraction of the time. Watch how it works:Key Benefits:
100% Secure: No internet connection required and no data is uploaded anywhere.
Zero Onboarding: Everything is handled inside the Excel environment you already use. No new software to learn.
Join the Early Access Program
Excel in Science — Validated Excel Tools for Pharmaceutical Analysis
Full refund within 30 days of purchase, no questions asked, if the tool does not meet your satisfaction.
Frequently Asked Questions
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The EIS Dissolution Analytics Add-in works with Microsoft 365
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The add-in supports up to 10 time points and up to 15 replicates per product. That covers typical dissolution profiles, including the 12 units per product that FDA and EMA expect for f2 similarity comparisons, with room to spare.
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The free trial gives you 7 days of access to try the add-in. The full version is an annual subscription, with access for one year from the date you subscribe.
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Yes. All calculations run locally on your computer, so your data never leaves your machine or gets uploaded to our servers.
Try It Before You Buy
Not ready to commit? Start with the free trial. Sign up below and we’ll send a limited-access version of the calculator directly to your inbox. Test it with your own lab data and see how it fits your workflow before making a decision.